Enzymes are key targets, and key components, of those tools, which need to be robust, easy-to-use, and compatible with automation.
We are developing scalable, plug-and-play solutions that integrate with liquid handling systems using immobilized enzymes on our custom materials. Our first solution combines multiple enzymatic pathways in one integrated platform to mimic a diversity of human metabolism in a high-throughput fashion for drug development and safety testing.
With 80,000 consumer chemicals currently in use, and 2,000 being added every year, thorough testing is key to consumer safety. With new standards to increase customer safety, all these chemicals must be assessed for the effects of both the chemicals and their metabolites. To introduce this step seamlessly to high-throughput safety screens, Zymtronix is developing compatible metabolic assays using immobilized enzymes.
ZymTox is a metabolic assay that is compatible with existing high-throughput screening technology. Combinations of metabolic enzymes can be included in a single screen to mimic human metabolism and thoroughly test the metabolites of consumer chemicals.
ZymTox takes advantage of the universality of our magnetic materials to immobilize combinations of multiple metabolic enzymes. Consumer chemicals can then be applied to the ZymTox assay and the metabolites tested with high-throughput screening. This solution means that the greater need for chemical screening can be met easily, with little disruption to current infrastructure.
We are always developing ways to service key industries and bring next wave biocatalysis to new markets. Contact us to learn more about ZymTox and our services for the safety testing market.
